BlackBerry cut nearly 100 jobs Monday. That follows 250 jobs eliminated last month.
"This week's employee reductions demonstrate another step forward to scale our company correctly for new opportunities in mobile computing," the Waterloo, Ont.-based company said in a statement Tuesday.
The company announced restructuring plans last year that would include cutting about 5,000 employees.
"Our evolution as a company is ongoing and is in no way easy, but we are realistic about what is required to move our transformation forward in a timely manner. We will be as transparent as possible as our plans evolve."
The struggling smartphone maker said earlier this month it was weighing options that could include an outright sale.
BlackBerry has bled market share to Apple and phones using Google's Android operating system, and its new BlackBerry 10 smartphones have failed to gain traction with consumers.
--with files from Reuters